Ethanol → N-[1-(4-aminophenyl)pyrrolidin-3-yl]-N-methylacetamide

HRID 817247Notes

Reaction equation

HRID 817247 reaction equation
[CH3:1][N:2]([C:3]([CH3:4])=[O:5])[CH:6]1[CH2:7][N:8]([c:11]2[cH:12][cH:13][c:14]([N+:17]([O-:18])=[O:19])[cH:15][cH:16]2)[CH2:9][CH2:10]1.[CH3:20][CH2:21][OH:22].[CH3:23][CH2:24][O:25][C:26](=[O:27])[CH3:28].[OH-:29].[OH-:31].[Pd+2:30]>>[CH3:1][N:2]([C:3]([CH3:4])=[O:5])[CH:6]1[CH2:7][N:8]([c:11]2[cH:12][cH:13][c:14]([NH2:17])[cH:15][cH:16]2)[CH2:9][CH2:10]1

Participants

6

Reactant 5

HCID 702EthanolHCID 961Hydroxide2×HCID 8857Ethyl AcetateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 21105631N-methyl-N-[1-(4-nitrophenyl)pyrrolidin-3-yl]acetamide

Product 1

HCID 21105566N-[1-(4-aminophenyl)pyrrolidin-3-yl]-N-methylacetamide

Sources & evidence

ORD record
ord-aa8bd736471744e0b76fdca5aaaf1373
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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