Trifluoroacetic acid → N-(4-methyl-5-sulfamoylthiazol-2-yl)acetamide

HRID 817458Notes

Reaction equation

HRID 817458 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[c:10]([CH3:18])[n:11][c:12]([NH:14][C:15]([CH3:16])=[O:17])[s:13]1.[F:19][C:20]([F:21])([F:22])[C:23]([OH:24])=[O:25]>>[NH2:5][S:6](=[O:7])(=[O:8])[c:9]1[c:10]([CH3:18])[n:11][c:12]([NH:14][C:15]([CH3:16])=[O:17])[s:13]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 59257550N-{5-[(tert-Butylamino)sulfonyl]-4-methyl-1,3-thiazol-2-yl)acetamide

Product 1

HCID 3244062N-(4-methyl-5-sulfamoylthiazol-2-yl)acetamide

Sources & evidence

ORD record
ord-82e67c156005462ea8a3c16fb26ccd41
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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