Chloroform → 1-[4-(1-Aminoethyl)phenyl]-2-(tert-butylamino)ethan-1-ol
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][CH2:6][CH:7]([OH:8])[c:9]1[cH:10][cH:11][c:12]([CH:15]([CH3:16])[NH:17][C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:13][cH:14]1.[CH:32]([Cl:33])([Cl:34])[Cl:35].[OH:25][C:26]([C:27]([F:28])([F:29])[F:30])=[O:31]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][CH2:6][CH:7]([OH:8])[c:9]1[cH:10][cH:11][c:12]([CH:15]([CH3:16])[NH2:17])[cH:13][cH:14]1Participants
4
Sources & evidence
- ORD record
- ord-d212166dcefa4ca5ad622f394abb8e3e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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