Dichloromethane → N-[(4-Chlorophenyl)methyl]-N-(2-methylpropyl)pyrrolidin-3-amine

HRID 818240Notes

Reaction equation

HRID 818240 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([N:13]([CH2:14][CH:15]([CH3:16])[CH3:17])[CH2:18][c:19]2[cH:20][cH:21][c:22]([Cl:25])[cH:23][cH:24]2)[CH2:11][CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[Cl:33][CH2:34][Cl:35].[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[NH:8]1[CH2:9][CH:10]([N:13]([CH2:14][CH:15]([CH3:16])[CH3:17])[CH2:18][c:19]2[cH:20][cH:21][c:22]([Cl:25])[cH:23][cH:24]2)[CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 667581663-[(4-Chloro-benzyl)-isobutyl-amino]-pyrrolidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 23136981N-[(4-Chlorophenyl)methyl]-N-(2-methylpropyl)pyrrolidin-3-amine

Sources & evidence

ORD record
ord-c1d2ef337bf741b6bb1f67daa754faf2
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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