Hydrochloric Acid → 5-Biphenyl-4-yl-3-hydroxy-pentanoic acid tert-butyl ester
Reaction equation
[BH4-:1].[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8]([CH2:9][C:10]([CH2:11][CH2:12][c:13]1[cH:14][cH:15][c:16](-[c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:17][cH:18]1)=[O:25])=[O:26].[CH3:28][OH:29].[ClH:27].[Na+:2]>>[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8]([CH2:9][CH:10]([CH2:11][CH2:12][c:13]1[cH:14][cH:15][c:16](-[c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:17][cH:18]1)[OH:25])=[O:26]Participants
6
Sources & evidence
- ORD record
- ord-0e3d3d9a11ec40d58bac2c0579f4cee0
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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