HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 818632Generated: October 30, 2026
1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide → 4-bromo-1'-[3-[2-(trifluoromethyl)phenyl]prop-2-enoyl]spiro[2H-isoindole-3,4'-piperidine]-1-one
https://huagongshe.com/reaction/818632
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide | HCID 15908 | — |
| Reactant | 3-(2-(Trifluoromethyl)phenyl)-2-propenoic acid | HCID 74939 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | 7-Bromospiro[isoindoline-1,4'-piperidin]-3-one | HCID 58295726 | — |
| Product | 4-bromo-1'-[3-[2-(trifluoromethyl)phenyl]prop-2-enoyl]spiro[2H-isoindole-3,4'-piperidine]-1-one | HCID 67223703 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Test data from https://doi.org/10.1039/C8SC04228D |
|---|
| ORD ID | ord-cec2481cd3ed4e5f8d0882b70d5796a0 |
|---|
| Source note | Test data from https://doi.org/10.1039/C8SC04228D |
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