Hydrochloric Acid → 5-[4,5-bis(4-chlorophenyl)-1-[4-[2-(methanesulfonamido)ethyl]piperazine-1-carbonyl]-4,5-dimethylimidazol-2-yl]-N-tert-butyl-2-chloro-4-ethoxybenzenesulfonamide

HRID 818653Notes

Reaction equation

HRID 818653 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[c:10]([Cl:42])[cH:11][c:12]([O:39][CH2:40][CH3:41])[c:13]([C:15]2=[N:19][C:18]([CH3:20])([c:21]3[cH:22][cH:23][c:24]([Cl:27])[cH:25][cH:26]3)[C:17]([CH3:28])([c:29]3[cH:30][cH:31][c:32]([Cl:35])[cH:33][cH:34]3)[N:16]2[C:36](=[O:37])[Cl:38])[cH:14]1.[ClH:43].[ClH:44].[N:45]1([CH2:51][CH2:52][NH:53][S:54](=[O:55])(=[O:56])[CH3:57])[CH2:46][CH2:47][NH:48][CH2:49][CH2:50]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[c:10]([Cl:42])[cH:11][c:12]([O:39][CH2:40][CH3:41])[c:13]([C:15]2=[N:19][C:18]([CH3:20])([c:21]3[cH:22][cH:23][c:24]([Cl:27])[cH:25][cH:26]3)[C:17]([CH3:28])([c:29]3[cH:30][cH:31][c:32]([Cl:35])[cH:33][cH:34]3)[N:16]2[C:36](=[O:37])[N:48]2[CH2:47][CH2:46][N:45]([CH2:51][CH2:52][NH:53][S:54](=[O:55])(=[O:56])[CH3:57])[CH2:50][CH2:49]2)[cH:14]1

Participants

4

Reactant 3

HCID 313Hydrochloric Acid2×HCID 23573807N-[2-(1-Piperazinyl)ethyl]methanesulfonamideHCID 72455726rac-(4S*,5R*)-2-(5-tert-Butylsulfamoyl-4-chloro-2-ethoxyphenyl)-4,5-bis-(4-chlorophenyl)-4,5-dimethyl-4,5-dihydroimidazole-1-carbonyl chloride

Product 1

HCID 1784666865-[4,5-bis(4-chlorophenyl)-1-[4-[2-(methanesulfonamido)ethyl]piperazine-1-carbonyl]-4,5-dimethylimidazol-2-yl]-N-tert-butyl-2-chloro-4-ethoxybenzenesulfonamide

Sources & evidence

ORD record
ord-31c2ff24b93c4d749fd900c8a2eb4eab
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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