Hydrochloric Acid → 5-(1-Phenylcyclopropyl)thiazolo[5,4-b]pyridine-2-carboxylic acid

HRID 818713Notes

Reaction equation

HRID 818713 reaction equation
[CH3:1][C:2]([O-:3])([CH3:4])[CH3:5].[CH3:34][S:35]([CH3:36])=[O:37].[CH3:8][S+:9]([CH3:10])([CH3:11])=[O:12].[ClH:38].[I-:7].[K+:6].[Na+:33].[c:13]1([C:19](=[CH2:20])[c:21]2[cH:22][cH:23][c:24]3[c:25]([n:26]2)[s:27][c:28]([C:30](=[O:31])[O-:32])[n:29]3)[cH:14][cH:15][cH:16][cH:17][cH:18]1>>[CH2:1]1[C:19]([c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)([c:21]2[cH:22][cH:23][c:24]3[c:25]([n:26]2)[s:27][c:28]([C:30](=[O:31])[OH:32])[n:29]3)[CH2:20]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 679Dimethyl SulfoxideHCID 813Potassium CationHCID 923Sodium ionHCID 30165Iodide IonHCID 74499TrimethylsulfoxoniumHCID 45749132-Methylpropan-2-olateHCID 178435897HCID 178435897, compound

Product 1

HCID 671116745-(1-Phenylcyclopropyl)thiazolo[5,4-b]pyridine-2-carboxylic acid

Sources & evidence

ORD record
ord-837f164ae79a4f3983b6f119d788a4e4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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