2-Morpholinoethylamine → 2-Bromo-5-(2-fluoro-4-iodo-phenylamino)-N-(2-morpholin-4-yl-ethyl)-isonicotinamide

HRID 818771Notes

Reaction equation

HRID 818771 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[c:8]([NH:11][c:12]2[c:13]([F:19])[cH:14][c:15]([I:18])[cH:16][cH:17]2)[cH:9][n:10]1.[O:20]1[CH2:21][CH2:22][N:23]([CH2:26][CH2:27][NH2:28])[CH2:24][CH2:25]1>>[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:7])[NH:28][CH2:27][CH2:26][N:23]2[CH2:22][CH2:21][O:20][CH2:25][CH2:24]2)[c:8]([NH:11][c:12]2[c:13]([F:19])[cH:14][c:15]([I:18])[cH:16][cH:17]2)[cH:9][n:10]1

Participants

3

Reactant 2

HCID 4082852-MorpholinoethylamineHCID 576496492-Bromo-5-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid

Product 1

HCID 116853762-Bromo-5-(2-fluoro-4-iodo-phenylamino)-N-(2-morpholin-4-yl-ethyl)-isonicotinamide

Sources & evidence

ORD record
ord-c09696722dea4b259af7cc158a13438f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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