Water → 1,1-dimethylethyl 4-{[(3-(1,1-dimethylethyl)-6-fluoro-1-methyl-9-(methyloxy)-5-{3-methyl-4-[(phenylmethyl)oxy]phenyl}-3H-pyrazolo[3,4-c]isoquinolin-8-yl)oxy]methyl}piperidine-1-carboxylate

HRID 818888Notes

Reaction equation

[C:38](=[O:39])([O-:40])[O-:41].[CH3:1][C:2]([CH3:3])([CH3:4])[n:5]1[n:6][c:7]([CH3:37])[c:8]2[c:9]1[n:10][c:11](-[c:22]1[cH:23][c:24]([CH3:36])[c:25]([O:28][CH2:29][c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:26][cH:27]1)[c:12]1[c:13]([F:21])[cH:14][c:15]([OH:20])[c:16]([O:18][CH3:19])[c:17]21.[CH3:44][S:45]([O:46][CH2:49][CH:50]1[CH2:51][CH2:52][N:53]([C:56](=[O:57])[O:58][C:59]([CH3:60])([CH3:61])[CH3:62])[CH2:54][CH2:55]1)(=[O:47])=[O:48].[Cs+:42].[Cs+:43].[O:64]=[CH:65][N:66]([CH3:67])[CH3:68].[OH2:63]>>[CH3:1][C:2]([CH3:3])([CH3:4])[n:5]1[n:6][c:7]([CH3:37])[c:8]2[c:9]1[n:10][c:11](-[c:22]1[cH:23][c:24]([CH3:36])[c:25]([O:28][CH2:29][c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:26][cH:27]1)[c:12]1[c:13]([F:21])[cH:14][c:15]([O:20][CH2:49][CH:50]3[CH2:51][CH2:52][N:53]([C:56](=[O:57])[O:58][C:59]([CH3:60])([CH3:61])[CH3:62])[CH2:54][CH2:55]3)[c:16]([O:18][CH3:19])[c:17]21