Dichloromethane → 2-[1-[[2-Chloro-6-(trifluoromethyl)phenyl]methyl]-3-[[1-(2-fluoropentyl)piperidin-4-yl]carbamoyl]-4-methylpyrrolidin-3-yl]acetic acid
Reaction equation
[Cl:1][c:2]1[c:3]([CH2:12][N:13]2[CH2:14][C:15]([C:19]([NH:20][CH:21]3[CH2:22][CH2:23][N:24]([CH2:27][CH:28]([CH2:29][CH2:30][CH3:31])[F:32])[CH2:25][CH2:26]3)=[O:33])([CH2:34][C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH:16]([CH3:18])[CH2:17]2)[c:4]([C:8]([F:9])([F:10])[F:11])[cH:5][cH:6][cH:7]1.[Cl:49][CH2:50][Cl:51].[OH:42][C:43]([C:44]([F:45])([F:46])[F:47])=[O:48]>>[Cl:1][c:2]1[c:3]([CH2:12][N:13]2[CH2:14][C:15]([C:19]([NH:20][CH:21]3[CH2:22][CH2:23][N:24]([CH2:27][CH:28]([CH2:29][CH2:30][CH3:31])[F:32])[CH2:25][CH2:26]3)=[O:33])([CH2:34][C:35](=[O:36])[OH:37])[CH:16]([CH3:18])[CH2:17]2)[c:4]([C:8]([F:9])([F:10])[F:11])[cH:5][cH:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-8389920a4b60438184183ab2a95e5070
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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