Methanol → [2-(4-Nitro-phenyl)-ethyl]-[2-(4-phenyl-piperazin-1-yl)-ethyl]-amine

HRID 819448Notes

Reaction equation

HRID 819448 reaction equation
[BH4-:1].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:30][OH:31].[N+:3](=[O:4])([O-:5])[c:6]1[cH:7][cH:8][c:9]([CH2:12][C:13](=[O:14])[NH:15][CH2:16][CH2:17][N:18]2[CH2:19][CH2:20][N:21]([c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[CH2:22][CH2:23]2)[cH:10][cH:11]1.[Na+:2]>>[N+:3](=[O:4])([O-:5])[c:6]1[cH:7][cH:8][c:9]([CH2:12][CH2:13][NH:15][CH2:16][CH2:17][N:18]2[CH2:19][CH2:20][N:21]([c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[CH2:22][CH2:23]2)[cH:10][cH:11]1

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 8028TetrahydrofuranHCID 28123BorohydrideHCID 222613202-(4-nitrophenyl)-N-(2-(4-phenylpiperazin-1-yl)ethyl)acetamide

Product 1

HCID 22261321[2-(4-Nitro-phenyl)-ethyl]-[2-(4-phenyl-piperazin-1-yl)-ethyl]-amine

Sources & evidence

ORD record
ord-ce8f26b39e1f458ab898803168d9b092
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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