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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 819673Generated: October 27, 2026

1,2-Dichloroethane → 5-bromo-N-(2-fluoro-ethyl)-nicotinamide

https://huagongshe.com/reaction/819673

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
Reactant2-FluoroethylamineHCID 9996—
Reactant4-(Dimethylamino)pyridineHCID 14284—
Reactant5-Bromonicotinic acidHCID 88707—
Product5-bromo-N-(2-fluoro-ethyl)-nicotinamideHCID 86004357—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-6f3eecff9b20412dba33c749a4717604
Source noteTest data from https://doi.org/10.1039/C8SC04228D