1,2-Dichloroethane → 5-bromo-N-(2-fluoro-ethyl)-nicotinamide
Reaction equation
[Br:1][c:2]1[cH:3][n:4][cH:5][c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[CH2:15]([Cl:16])[CH2:17][Cl:18].[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[CH3:27][N:28]([c:29]1[cH:30][cH:31][n:32][cH:33][cH:34]1)[CH3:35].[Cl:36][CH2:37][Cl:38].[ClH:19].[F:11][CH2:12][CH2:13][NH2:14]>>[Br:1][c:2]1[cH:3][n:4][cH:5][c:6]([C:7](=[O:9])[NH:14][CH2:13][CH2:12][F:11])[cH:10]1Participants
8
Sources & evidence
- ORD record
- ord-6f3eecff9b20412dba33c749a4717604
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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