Methyl iodide → 2,4-Dichloro-5-methyl-7H-pyrrolo(2,3-d)pyrimidine

HRID 819686Notes

Reaction equation

HRID 819686 reaction equation
[Br:1][c:2]1[cH:3][nH:4][c:5]2[n:6][c:7]([Cl:12])[n:8][c:9]([Cl:11])[c:10]12.[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[CH3:13][CH2:14][CH2:15][CH2:16][Li:17].[CH3:18][I:19]>>[c:2]1([CH3:13])[cH:3][nH:4][c:5]2[n:6][c:7]([Cl:12])[n:8][c:9]([Cl:11])[c:10]12

Participants

5

Reactant 4

HCID 6328Methyl iodideHCID 8028TetrahydrofuranHCID 579904405-Bromo-2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidineHCID 178418339Butyllithium

Product 1

HCID 529828092,4-Dichloro-5-methyl-7H-pyrrolo(2,3-d)pyrimidine

Sources & evidence

ORD record
ord-cee4a09da13e460a9723f18b5b5fb5a3
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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