HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 81971Generated: October 25, 2026
Acetonitrile → HCID 178436230, compound
https://huagongshe.com/reaction/81971
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | N-(2,6-diethylphenyl)-8-iodo-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | HCID 86653101 | — |
| Product | HCID 178436230 | HCID 178436230 | — |
Reaction Steps
N-(2,6-diethylphenyl)-8-iodo-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (500 mg, 1.01 mmol) was dissolved in CH3CN (3 ml) and treated with trans-1,4-diaminecyclohexane (346 mg, 303 mmol). The mixture was heated at 110° C. for 10 minutes under microwave irradiation. The solvent was removed under reduced pressure and the crude was purified by column chromatography to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08846701B2 |
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| Source dataset | uspto-grants-2014_09 |
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| ORD ID | ord-a35ce91e47554129a75bad4efef177c3 |
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| Source note | uspto-grants-2014_09 |
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