Tetrahydrofuran → 4-(3-tert-Butyl-5-{3-[2-fluoro-4-(2-methyl-pyridin-4-yloxy)phenyl]ureido}pyrazol-1-yl)-2-methyl-N-(2-morpholin-4-yl-ethyl)benzene-sulfonamide
Reaction equation
[CH2:46]1[CH2:48][CH2:47][CH2:49][O:50]1.[F:30][c:31]1[c:32]([NH2:45])[cH:33][cH:34][c:35]([O:37][c:38]2[cH:39][c:40]([CH3:44])[n:41][cH:42][cH:43]2)[cH:36]1.[NH2:1][c:2]1[cH:3][c:4]([C:26]([CH3:27])([CH3:28])[CH3:29])[n:5][n:6]1-[c:7]1[cH:8][c:9]([CH3:25])[c:10]([S:13](=[O:14])(=[O:15])[NH:16][CH2:17][CH2:18][N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[cH:11][cH:12]1>>[NH:1]([c:2]1[cH:3][c:4]([C:26]([CH3:27])([CH3:28])[CH3:29])[n:5][n:6]1-[c:7]1[cH:8][c:9]([CH3:25])[c:10]([S:13](=[O:14])(=[O:15])[NH:16][CH2:17][CH2:18][N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[cH:11][cH:12]1)[C:49]([NH:45][c:32]1[c:31]([F:30])[cH:36][c:35]([O:37][c:38]2[cH:39][c:40]([CH3:44])[n:41][cH:42][cH:43]2)[cH:34][cH:33]1)=[O:50]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-bebed441db174823bee4fdab71a818fb
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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