Potassium Cation → 2-Bromo-4-{[(2,4-dimethoxy-benzyl)-ethoxycarbonylmethyl-amino]-methyl}-thiazole-5-carboxylic acid ethyl ester

HRID 819854Notes

Reaction equation

HRID 819854 reaction equation
[C:32](=[O:33])([O-:34])[O-:35].[CH2:14]([CH3:15])[O:16][C:17]([CH2:18][NH:19][CH2:20][c:21]1[c:22]([O:29][CH3:30])[cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]1)=[O:31].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([CH2:12][Br:13])[n:8][c:9]([Br:11])[s:10]1.[CH3:38][N:39]([CH3:40])[CH:41]=[O:42].[K+:36].[K+:37]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([CH2:12][N:19]([CH2:18][C:17]([O:16][CH2:14][CH3:15])=[O:31])[CH2:20][c:21]2[c:22]([O:29][CH3:30])[cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]2)[n:8][c:9]([Br:11])[s:10]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 19895532Ethyl 2-(2,4-dimethoxybenzylamino)acetateHCID 68428140Ethyl 2-bromo-4-(bromomethyl)thiazole-5-carboxylate

Product 1

HCID 684264542-Bromo-4-{[(2,4-dimethoxy-benzyl)-ethoxycarbonylmethyl-amino]-methyl}-thiazole-5-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-f076be47607c4f76bb533e26d965f412
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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