Sulfuric Acid → 2-(4-Chlorophenyl)-2-(4-iodophenyl)morpholine

HRID 819858Notes

Reaction equation

HRID 819858 reaction equation
[CH3:30][CH2:31][O:32][C:33](=[O:34])[CH3:35].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]([CH2:9][NH:10][CH2:11][CH2:12][OH:13])([OH:14])[c:15]2[cH:16][cH:17][c:18]([I:21])[cH:19][cH:20]2)[cH:6][cH:7]1.[Cl:27][CH2:28][Cl:29].[S:22](=[O:23])(=[O:24])([OH:25])[OH:26]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([c:15]3[cH:16][cH:17][c:18]([I:21])[cH:19][cH:20]3)[CH2:9][NH:10][CH2:11][CH2:12][O:14]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 1118Sulfuric AcidHCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 593319671-(4-Chloro-phenyl)-2-(2-hydroxy-ethylamino)-1-(4-iodo-phenyl)-ethanol

Product 1

HCID 593319352-(4-Chlorophenyl)-2-(4-iodophenyl)morpholine

Sources & evidence

ORD record
ord-9db590cefff8472bbde538c6249c564f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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