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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 819951Generated: October 30, 2026

Methanol → (+)-N4-(3,4-difluorophenyl)-N2-(2,3-dihydro-2-methoxycarbonylbenzofuran-5-yl)-5-fluoro-2,4-pyrimidinediamine

https://huagongshe.com/reaction/819951

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantMethyl 5-amino-2,3-dihydrobenzofuran-2-carboxylateHCID 22060823—
Reactant2-chloro-N4-(3,4-difluorophenyl)-5-fluoro-4-pyrimidineamineHCID 22061049—
Product(+)-N4-(3,4-difluorophenyl)-N2-(2,3-dihydro-2-methoxycarbonylbenzofuran-5-yl)-5-fluoro-2,4-pyrimidinediamineHCID 22060930—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-c0e4af761d354e78a40c9c3b18e7e6a3
Source noteTest data from https://doi.org/10.1039/C8SC04228D