HRID82001

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID143957

2-Morpholinoethyl isothiocyanate

C7H12N2OS

结构：COc1cc2c(NCC3CCOCC3)c(N)cnc2cc1-c1c(C)noc1C

HCID70981155

未命名化合物

PRODUCTS

生成物

结构：COc1cc2c(cc1-c1c(C)noc1C)ncc1nc(NCCN3CCOCC3)n(CC3CCOCC3)c12

HCID66571340

未命名化合物

收率 60%

PROCEDURE

实验过程

From 7-(3,5-dimethylisoxazol-4-yl)-6-methoxy-N4-((tetrahydro-2H-pyran-4-yl)methyl)quinoline-3,4-diamine (for a preparation see Intermediate 17) (70 mg) and 4-(2-isothiocyanatoethyl)morpholine (50 mg) to give the title compound as beige solid (57 mg, 60%). LCMS (formate) Rt 0.51 min, MH+ 521