Dimethylformamide → 5-Bromo-2-chloro-3-pyridinecarbonyl chloride

HRID 820207Notes

Reaction equation

HRID 820207 reaction equation
[Br:15][c:16]1[cH:17][n:18][c:19]([Cl:25])[c:20]([C:22]([OH:23])=[O:24])[cH:21]1.[Br:1][c:2]1[cH:3][n:4][c:5]([Cl:14])[c:6]([C:7](=[O:8])[N:9]([O:10][CH3:11])[CH3:12])[cH:13]1.[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[S:31]([Cl:32])([Cl:33])=[O:34]>>[Br:1][c:2]1[cH:3][n:4][c:5]([Cl:14])[c:6]([C:7](=[O:8])[Cl:25])[cH:13]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 27633425-Bromo-2-chloronicotinic acidHCID 568289985-Bromo-2-chloro-N-methoxy-N-methylnicotinamide

Product 1

HCID 126772955-Bromo-2-chloro-3-pyridinecarbonyl chloride

Sources & evidence

ORD record
ord-7e3a03a9e5dc4616b06923a0a45f4cdf
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…