Hydrochloric Acid → 3-[2-butyl-6-(trifluoromethyl)pyridin-3-yl]-N-[1-[3,5-difluoro-4-(methanesulfonamido)phenyl]ethyl]prop-2-ynamide
Reaction equation
[CH2:18]([CH2:19][CH2:20][CH3:21])[c:22]1[n:23][c:24]([C:33]([F:34])([F:35])[F:36])[cH:25][cH:26][c:27]1[C:28]#[C:29][C:30](=[O:31])[OH:32].[ClH:17].[NH2:1][CH:2]([CH3:3])[c:4]1[cH:5][c:6]([F:16])[c:7]([NH:11][S:12](=[O:13])(=[O:14])[CH3:15])[c:8]([F:10])[cH:9]1>>[NH:1]([CH:2]([CH3:3])[c:4]1[cH:5][c:6]([F:16])[c:7]([NH:11][S:12](=[O:13])(=[O:14])[CH3:15])[c:8]([F:10])[cH:9]1)[C:30]([C:29]#[C:28][c:27]1[c:22]([CH2:18][CH2:19][CH2:20][CH3:21])[n:23][c:24]([C:33]([F:34])([F:35])[F:36])[cH:25][cH:26]1)=[O:31]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a69e1b01df46468cb97fe79914d2354c
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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