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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 820379Generated: October 30, 2026

8-Chloro-6,7-difluoro-1-((1R,2S)-2-fluorocyclopropyl)--4-oxo-1,4-dihydroquinoline-3-carboxylic acid → 8-Chloro-7-[3-[(cyclopropylamino)methyl]-4-fluoropyrrolidin-1-yl]-6-fluoro-1-(2-fluorocyclopropyl)-4-oxoquinoline-3-carboxylic acid

https://huagongshe.com/reaction/820379

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Chloro-6,7-difluoro-1-((1R,2S)-2-fluorocyclopropyl)--4-oxo-1,4-dihydroquinoline-3-carboxylic acidHCID 19365042—
Reactant3-Pyrrolidinemethanamine,N-cyclopropyl-4-fluoro-,(3R,4S)-(9CI)HCID 23062073—
Product8-Chloro-7-[3-[(cyclopropylamino)methyl]-4-fluoropyrrolidin-1-yl]-6-fluoro-1-(2-fluorocyclopropyl)-4-oxoquinoline-3-carboxylic acidHCID 23125659—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-b43962a901484df6ada6a6aa57cdf5df
Source noteTest data from https://doi.org/10.1039/C8SC04228D