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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 820401Generated: October 27, 2026

Acetate → 5-(1-Butyn-1-yl)-3-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole

https://huagongshe.com/reaction/820401

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetateHCID 175—
ReactantNitrogenHCID 947—
ReactantCarbonate IonHCID 19660—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantFerrous cationHCID 27284—
Reactant1-ButynyltrimethylsilaneHCID 43926—
ReactantCesium cationHCID 104967—
ReactantAllyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 105144—
Reactant5-Bromo-3-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazoleHCID 66793297—
ReactantHCID 178420532HCID 178420532—
Product5-(1-Butyn-1-yl)-3-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazoleHCID 66793285—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-df85c26e56c54144a50c08fab2592b95
Source noteTest data from https://doi.org/10.1039/C8SC04228D