Acetate → 5-(1-Butyn-1-yl)-3-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([F:17])[n:6][n:7]([CH:11]3[O:12][CH2:13][CH2:14][CH2:15][CH2:16]3)[c:8]2[cH:9][cH:10]1.[C:18](=[O:19])([O-:20])[O-:21].[C:24](#[C:25][CH2:26][CH3:27])[Si:28]([CH3:29])([CH3:30])[CH3:31].[Cs+:22].[Cs+:23].[Cu:34][I:35].[Fe+2:81].[N:32]#[N:33].[O-:37][C:38]([CH3:39])=[O:40].[O-:41][C:42]([CH3:43])=[O:44].[Pd+2:36].[cH:45]1[cH:46][cH:47][c:48]([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c-:56]2[cH:57][cH:58][cH:59][cH:60]2)[cH:61][cH:62]1.[cH:63]1[cH:64][cH:65][c:66]([P:67]([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[c-:74]2[cH:75][cH:76][cH:77][cH:78]2)[cH:79][cH:80]1>>[c:2]1([C:24]#[C:25][CH2:26][CH3:27])[cH:3][c:4]2[c:5]([F:17])[n:6][n:7]([CH:11]3[O:12][CH2:13][CH2:14][CH2:15][CH2:16]3)[c:8]2[cH:9][cH:10]1Participants
11
Reactant 10
HCID 175Acetate2×
HCID 947Nitrogen
HCID 19660Carbonate Ion
HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)
HCID 27284Ferrous cation
HCID 439261-Butynyltrimethylsilane
HCID 104967Cesium cation2×
HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)
HCID 667932975-Bromo-3-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
HCID 178420532HCID 178420532, compound2×Product 1
Sources & evidence
- ORD record
- ord-df85c26e56c54144a50c08fab2592b95
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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