Sodium ion → 7-[4,4-bis(4-fluorophenyl)butyl]hexahydro-3,3-dimethyl-1H-oxazolo[3,4-a]pyrazine

HRID 820450Notes

Reaction equation

HRID 820450 reaction equation
[CH3:20][C:21]1([CH3:30])[O:22][CH2:23][CH:24]2[N:25]1[CH2:26][CH2:27][NH:28][CH2:29]2.[CH3:37][N:38]([CH3:39])[CH:40]=[O:41].[I:1][CH2:2][CH2:3][CH2:4][CH:5]([c:6]1[cH:7][cH:8][c:9]([F:12])[cH:10][cH:11]1)[c:13]1[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]1.[Na+:31].[Na+:32].[O-:33][C:34](=[O:35])[O-:36]>>[CH2:2]([CH2:3][CH2:4][CH:5]([c:6]1[cH:7][cH:8][c:9]([F:12])[cH:10][cH:11]1)[c:13]1[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]1)[N:28]1[CH2:27][CH2:26][N:25]2[C:21]([CH3:20])([CH3:30])[O:22][CH2:23][CH:24]2[CH2:29]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 1039681,1'-(4-Iodobutylidene)bis[4-fluorobenzene]HCID 212956453,3-Dimethylhexahydro-3H-[1,3]oxazolo[3,4-a]pyrazine

Product 1

HCID 212957107-[4,4-bis(4-fluorophenyl)butyl]hexahydro-3,3-dimethyl-1H-oxazolo[3,4-a]pyrazine

Sources & evidence

ORD record
ord-96efb17dd4be4a14a32e5d51f5c43d6f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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