Methanol → 1-(4-(3-Aminopyridin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)urea
Reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:32][OH:33].[F:1][c:2]1[cH:3][c:4]([NH:18][C:19](=[O:20])[NH:21][C:22]([CH2:23][c:24]2[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]2)=[O:31])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]([N+:15]([O-:16])=[O:17])[cH:11][n:12][cH:13][cH:14]1>>[F:1][c:2]1[cH:3][c:4]([NH:18][C:19](=[O:20])[NH:21][C:22]([CH2:23][c:24]2[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]2)=[O:31])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]([NH2:15])[cH:11][n:12][cH:13][cH:14]1Participants
4
Sources & evidence
- ORD record
- ord-50f79431578640aa84abc65eee50a841
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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