N-methyl-2-pyrrolidone → HCID 57441162, compound

HRID 820819Notes

Reaction equation

HRID 820819 reaction equation
[CH3:35][N:36]1[CH2:37][CH2:38][CH2:39][C:40]1=[O:41].[Cl:1][c:2]1[c:3](-[c:22]2[cH:23][c:24]([C:28]([F:29])([F:30])[F:31])[cH:25][cH:26][cH:27]2)[cH:4][c:5]([CH3:21])[c:6]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][CH:13]([N:16]3[CH2:17][CH2:18][CH2:19][CH2:20]3)[CH2:14][CH2:15]2)[n:7]1.[Na:32][C:33]#[N:34]>>[c:2]1([C:33]#[N:34])[c:3](-[c:22]2[cH:23][c:24]([C:28]([F:29])([F:30])[F:31])[cH:25][cH:26][cH:27]2)[cH:4][c:5]([CH3:21])[c:6]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][CH:13]([N:16]3[CH2:17][CH2:18][CH2:19][CH2:20]3)[CH2:14][CH2:15]2)[n:7]1

Participants

4

Reactant 3

HCID 13387N-methyl-2-pyrrolidoneHCID 44547211[6-Chloro-3-methyl-5-(3-trifluoromethyl-phenyl)-pyridin-2-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanoneHCID 178511850HCID 178511850, compound

Product 1

HCID 57441162HCID 57441162, compound

Sources & evidence

ORD record
ord-7bdb9d25d381494db2904640c647a58b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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