Nitric Acid → 7-nitro-3-(trifluoroacetyl)-2,3,4,5-tetrahydro-1H-1,5-methano-3-benzazepine

HRID 820981Notes

Reaction equation

HRID 820981 reaction equation
[CH:13]12[c:14]3[cH:15][cH:16][cH:17][cH:18][c:19]3[CH:20]([CH2:21][N:22]([C:24]([C:25]([F:26])([F:27])[F:28])=[O:29])[CH2:23]1)[CH2:30]2.[Cl:31][CH2:32][Cl:33].[OH:1][S:2]([C:3]([F:4])([F:5])[F:6])(=[O:7])=[O:8].[OH:9][N+:10]([O-:11])=[O:12]>>[O-:9][N+:10](=[O:12])[c:17]1[cH:16][cH:15][c:14]2[c:19]([cH:18]1)[CH:20]1[CH2:21][N:22]([C:24]([C:25]([F:26])([F:27])[F:28])=[O:29])[CH2:23][CH:13]2[CH2:30]1

Participants

5

Reactant 4

HCID 944Nitric AcidHCID 6344DichloromethaneHCID 62406Trifluoromethanesulfonic acidHCID 218647322,2,2-Trifluoro-1-(1,2,4,5-tetrahydro-3H-1,5-methano-3-benzazepin-3-yl)ethan-1-one

Product 1

HCID 218647057-nitro-3-(trifluoroacetyl)-2,3,4,5-tetrahydro-1H-1,5-methano-3-benzazepine

Sources & evidence

ORD record
ord-d3066845bbbb4b64bc97cd4792969fb8
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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