Potassium Cation → 1-Boc-4-(2-formylphenyl)piperazine

HRID 821050Notes

Reaction equation

HRID 821050 reaction equation
[C:10](=[O:11])([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[N:17]1[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]1.[Cu:34].[F:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][cH:7][cH:8][cH:9]1.[K+:23].[K+:24].[O-:25][C:26]([O-:27])=[O:28].[O:29]=[CH:30][N:31]([CH3:32])[CH3:33]>>[c:2]1([N:20]2[CH2:19][CH2:18][N:17]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:22][CH2:21]2)[c:3]([CH:4]=[O:5])[cH:6][cH:7][cH:8][cH:9]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 23978CopperHCID 67970o-FluorobenzaldehydeHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 64909901-Boc-4-(2-formylphenyl)piperazine

Sources & evidence

ORD record
ord-bbeefbb99db6455790c97459a13a324c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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