Sodium ion → 1-methyl-1H-pyrazole-4-sulfonic acid {2-[3'-(4-methoxymethyl-phenyl)-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl]-ethyl}-methyl-amide

HRID 821075Notes

Reaction equation

HRID 821075 reaction equation
[C:36]([O:37][BH-:38]([O:39][C:40](=[O:41])[CH3:42])[O:43][C:44](=[O:45])[CH3:46])(=[O:47])[CH3:48].[CH3:1][O:2][CH2:3][c:4]1[cH:5][cH:6][c:7](-[c:10]2[c:11]([N:16]3[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]3)[n:12][cH:13][cH:14][n:15]2)[cH:8][cH:9]1.[CH3:22][N:23]([S:24](=[O:25])(=[O:26])[c:27]1[cH:28][n:29][n:30]([CH3:32])[cH:31]1)[CH2:33][CH:34]=[O:35].[CH3:52][CH:53]1[CH2:54][CH2:55][CH2:56][O:57]1.[Na+:49].[Na+:51].[OH-:50]>>[CH3:1][O:2][CH2:3][c:4]1[cH:5][cH:6][c:7](-[c:10]2[c:11]([N:16]3[CH2:17][CH2:18][N:19]([CH2:34][CH2:33][N:23]([CH3:22])[S:24](=[O:25])(=[O:26])[c:27]4[cH:28][n:29][n:30]([CH3:32])[cH:31]4)[CH2:20][CH2:21]3)[n:12][cH:13][cH:14][n:15]2)[cH:8][cH:9]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 961HydroxideHCID 73012-MethyltetrahydrofuranHCID 2724942TriacetoxyborohydrideHCID 673675443'-(4-Methoxymethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinylHCID 866402111-Methyl-1H-pyrazole-4-sulfonic acid methyl-(2-oxo-ethyl)-amide

Product 1

HCID 251833521-methyl-1H-pyrazole-4-sulfonic acid {2-[3'-(4-methoxymethyl-phenyl)-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl]-ethyl}-methyl-amide

Sources & evidence

ORD record
ord-3eca1fc88b624b6e840dac61ab5a6c54
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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