1-Ethylpiperazine → methyl 4-methyl-3-[6-(4-ethylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzoate

HRID 821084Notes

Reaction equation

HRID 821084 reaction equation
[Br:9][c:10]1[cH:11][c:12]2[c:13](=[O:31])[n:14](-[c:20]3[cH:21][c:22]([C:23](=[O:24])[O:25][CH3:26])[cH:27][cH:28][c:29]3[CH3:30])[cH:15][n:16][c:17]2[cH:18][cH:19]1.[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][NH:6][CH2:7][CH2:8]1>>[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][N:6]([c:10]2[cH:11][c:12]3[c:13](=[O:31])[n:14](-[c:20]4[cH:21][c:22]([C:23](=[O:24])[O:25][CH3:26])[cH:27][cH:28][c:29]4[CH3:30])[cH:15][n:16][c:17]3[cH:18][cH:19]2)[CH2:7][CH2:8]1

Participants

3

Reactant 2

HCID 791961-EthylpiperazineHCID 66919066Methyl 3-(6-bromo-4-oxoquinazolin-3(4H)-yl)-4-methylbenzoate

Product 1

HCID 68604407methyl 4-methyl-3-[6-(4-ethylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzoate

Sources & evidence

ORD record
ord-ee9f3f9602314eb5989bba6e7806e41e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…