Tetrahydrofuran → 5-bromo-1-[(4-{[1-(trifluoromethyl)cyclopropyl]methyl}-1-trityl-1H-imidazol-2-yl)methyl]indan-1-ol

HRID 821113Notes

Reaction equation

[Br:39][c:40]1[cH:41][c:42]2[c:46]([cH:47][cH:48]1)[C:45](=[O:49])[CH2:44][CH2:43]2.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH3:6][c:7]1[n:8]([C:20]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[cH:9][c:10]([CH2:12][C:13]2([C:16]([F:17])([F:18])[F:19])[CH2:14][CH2:15]2)[n:11]1>>[CH2:6]([c:7]1[n:8]([C:20]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[cH:9][c:10]([CH2:12][C:13]2([C:16]([F:17])([F:18])[F:19])[CH2:14][CH2:15]2)[n:11]1)[C:45]1([OH:49])[CH2:44][CH2:43][c:42]2[cH:41][c:40]([Br:39])[cH:48][cH:47][c:46]21