HRID821113

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID520695

5-Bromo-1-indanone

C9H7BrO

结构：Cc1nc(CC2(C(F)(F)F)CC2)cn1C(c1ccccc1)(c1ccccc1)c1ccccc1

HCID59162038

未命名化合物

HCID178418339

Butyllithium

C4H9Li

PRODUCTS

生成物

结构：OC1(Cc2nc(CC3(C(F)(F)F)CC3)cn2C(c2ccccc2)(c2ccccc2)c2ccccc2)CCc2cc(Br)ccc21

HCID66705672

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3834d84eb5474d17afef7a9f73a07e86
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[Br:39][c:40]1[cH:41][c:42]2[c:46]([cH:47][cH:48]1)[C:45](=[O:49])[CH2:44][CH2:43]2.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH3:6][c:7]1[n:8]([C:20]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[cH:9][c:10]([CH2:12][C:13]2([C:16]([F:17])([F:18])[F:19])[CH2:14][CH2:15]2)[n:11]1>>[CH2:6]([c:7]1[n:8]([C:20]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[cH:9][c:10]([CH2:12][C:13]2([C:16]([F:17])([F:18])[F:19])[CH2:14][CH2:15]2)[n:11]1)[C:45]1([OH:49])[CH2:44][CH2:43][c:42]2[cH:41][c:40]([Br:39])[cH:48][cH:47][c:46]21