Formic Acid → Iguratimod

HRID 821202Notes

Reaction equation

HRID 821202 reaction equation
[CH2:42]([Cl:43])[Cl:44].[CH3:4][C:5]([O:6][C:7](=[O:8])[CH3:9])=[O:10].[CH:1](=[O:2])[OH:3].[CH:35]([O:36][CH:37]([CH3:38])[CH3:39])([CH3:40])[CH3:41].[NH2:11][c:12]1[cH:13][o:14][c:15]2[c:16]([c:17]1=[O:18])[cH:19][c:20]([O:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)[c:21]([NH:23][S:24](=[O:25])(=[O:26])[CH3:27])[cH:22]2>>[CH:1](=[O:2])[NH:11][c:12]1[cH:13][o:14][c:15]2[c:16]([c:17]1=[O:18])[cH:19][c:20]([O:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)[c:21]([NH:23][S:24](=[O:25])(=[O:26])[CH3:27])[cH:22]2

Participants

6

Reactant 5

HCID 284Formic AcidHCID 6344DichloromethaneHCID 7914Diisopropyl EtherHCID 7918Acetic AnhydrideHCID 10783765HCID 10783765, compound

Product 1

HCID 124246Iguratimod

Sources & evidence

ORD record
ord-9b9c167f1ca14f718052b7659bb67286
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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