Dimethylformamide → 1-(4-(4-(5-Chloro-4-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2-ylamino)-2,5-dimethylphenyl)piperidin-1-yl)-3-morpholinopropan-1-one
Reaction equation
[CH2:34]1[CH2:35][O:36][CH2:37][CH2:38][NH:39]1.[Cl:1][c:2]1[c:3]([NH:27][c:28]2[n:29][nH:30][c:31]([CH3:33])[cH:32]2)[n:4][c:5]([NH:8][c:9]2[cH:10][c:11]([CH3:26])[c:12]([CH:16]3[CH2:17][CH2:18][N:19]([C:22]([CH:23]=[CH2:24])=[O:25])[CH2:20][CH2:21]3)[cH:13][c:14]2[CH3:15])[n:6][cH:7]1.[O:40]=[CH:41][N:42]([CH3:43])[CH3:44]>>[Cl:1][c:2]1[c:3]([NH:27][c:28]2[n:29][nH:30][c:31]([CH3:33])[cH:32]2)[n:4][c:5]([NH:8][c:9]2[cH:10][c:11]([CH3:26])[c:12]([CH:16]3[CH2:17][CH2:18][N:19]([C:22]([CH2:23][CH2:24][N:39]4[CH2:34][CH2:35][O:36][CH2:37][CH2:38]4)=[O:25])[CH2:20][CH2:21]3)[cH:13][c:14]2[CH3:15])[n:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d3b2cf11ba5e4a51ac2ee5d3ba9d03f1
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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