4-Hydroxybenzyl Alcohol → [4-(2-Piperidin-1-ylethoxy)phenyl]methanol

HRID 821291Notes

Reaction equation

HRID 821291 reaction equation
[CH3:10][c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1.[Cl:18][CH2:19][CH2:20][N:21]1[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]1.[ClH:17].[Na+:28].[OH-:27].[OH:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][OH:7])[cH:8][cH:9]1>>[O:1]([c:2]1[cH:3][cH:4][c:5]([CH2:6][OH:7])[cH:8][cH:9]1)[CH2:19][CH2:20][N:21]1[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]1

Participants

7

Reactant 6

HCID 1254-Hydroxybenzyl AlcoholHCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 1140TolueneHCID 748271-(2-Chloroethyl)piperidine

Product 1

HCID 9816107[4-(2-Piperidin-1-ylethoxy)phenyl]methanol

Sources & evidence

ORD record
ord-24aa18b8079a4b709bee1e3ca16ee335
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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