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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 82136Generated: October 28, 2026

(2-amino-7-tert-butyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(5-amino-pyridin-3-yl)-methanone → HCID 70817726, compound

https://huagongshe.com/reaction/82136

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-amino-7-tert-butyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(5-amino-pyridin-3-yl)-methanoneHCID 70817234—
Reactant2-(4-Cyclopropyl-1H-pyrazol-1-yl)acetic acidHCID 84731614—
ProductHCID 70817726HCID 70817726—

Reaction Steps

The title compound was prepared according to the method described for Example 1 using (2-Amino-7-tert-butyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(5-amino-pyridin-3-yl)-methanone (see Preparation 65) and (4-cyclopropyl-pyrazol-1-yl)-acetic acid to afford the title compound as a pale yellow solid in 16% yield, 12 mg. LCMS (System 10): Rt=2.80 min; m/z 459 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846698B2
Source datasetuspto-grants-2014_09
ORD IDord-ebdda26fdef14cc1a3a12c7dc3c415bf
Source noteuspto-grants-2014_09