4-t-Butylbenzenesulfonyl chloride → 8-Iodo-2-(trifluoromethyl)-6-{[4-(trifluoromethyl)phenyl]sulfonyl}-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepine

HRID 821361Notes

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:32]([cH:33]1)[N:18]([S:19]([c:20]1[cH:21][cH:22][c:23]([C:24]([CH3:25])([CH3:26])[CH3:27])[cH:28][cH:29]1)(=[O:30])=[O:31])[CH2:17][c:16]1[c:7]([n:8][c:9]([C:10]([F:11])([F:12])[F:13])[cH:14][cH:15]1)[NH:6]2.[Br:68][c:69]1[cH:70][cH:71][c:72]2[c:86]([cH:87]1)[NH:85][CH2:84][c:83]1[c:74]([n:75][c:76]([C:77]([F:78])([F:79])[F:80])[cH:81][cH:82]1)[NH:73]2.[C:88]([c:89]1[cH:90][cH:91][c:92]([S:93]([Cl:94])(=[O:95])=[O:96])[cH:97][cH:98]1)([CH3:99])([CH3:100])[CH3:101].[F:54][C:55]([c:56]1[cH:57][cH:58][c:59]([S:62](=[O:63])(=[O:64])[Cl:65])[cH:60][cH:61]1)([F:66])[F:67].[I:34][c:35]1[cH:36][cH:37][c:38]2[c:39]([cH:53]1)[NH:40][CH2:41][c:42]1[c:43]([n:45][c:46]([C:49]([F:50])([F:51])[F:52])[cH:47][cH:48]1)[NH:44]2>>[I:34][c:35]1[cH:36][cH:37][c:38]2[c:39]([cH:53]1)[N:40]([S:62]([c:59]1[cH:58][cH:57][c:56]([C:55]([F:54])([F:66])[F:67])[cH:61][cH:60]1)(=[O:63])=[O:64])[CH2:41][c:42]1[c:43]([n:45][c:46]([C:49]([F:50])([F:51])[F:52])[cH:47][cH:48]1)[NH:44]2