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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 821361Generated: October 25, 2026

4-t-Butylbenzenesulfonyl chloride → 8-Iodo-2-(trifluoromethyl)-6-{[4-(trifluoromethyl)phenyl]sulfonyl}-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepine

https://huagongshe.com/reaction/821361

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-t-Butylbenzenesulfonyl chlorideHCID 139882—
Reactant4-(Trifluoromethyl)benzenesulfonyl chlorideHCID 2777399—
Reactant8-bromo-6-[(4-tert-butylphenyl)sulfonyl]-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepineHCID 59618636—
Reactant8-iodo-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepineHCID 66901596—
Reactant8-bromo-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepineHCID 66901653—
Product8-Iodo-2-(trifluoromethyl)-6-{[4-(trifluoromethyl)phenyl]sulfonyl}-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepineHCID 86649041—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-b4b3af83b1434a5985d5d44449573729
Source noteTest data from https://doi.org/10.1039/C8SC04228D