Hydrochloric Acid → Tert-butyl 3-(4-(5-(1-phenylcyclopropyl)-thiazolo[5,4-b]pyridin-2-yl)phenylamino)propanoate

HRID 821441Notes

Reaction equation

[CH3:1][C:2]([CH3:3])([O-:4])[CH3:5].[CH3:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[ClH:32].[I:7][c:8]1[cH:9][cH:10][c:11](-[c:14]2[s:15][c:16]3[n:17][c:18]([C:23]4([c:26]5[cH:27][cH:28][cH:29][cH:30][cH:31]5)[CH2:24][CH2:25]4)[cH:19][cH:20][c:21]3[n:22]2)[cH:12][cH:13]1.[NH2:33][CH2:34][CH2:35][C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42].[Na+:6].[O:52]=[C:53]([CH:54]=[CH:55][c:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1)[CH:62]=[CH:63][c:64]1[cH:65][cH:66][cH:67][cH:68][cH:69]1.[O:70]=[C:71]([CH:72]=[CH:73][c:74]1[cH:75][cH:76][cH:77][cH:78][cH:79]1)[CH:80]=[CH:81][c:82]1[cH:83][cH:84][cH:85][cH:86][cH:87]1.[O:88]=[C:89]([CH:90]=[CH:91][c:92]1[cH:93][cH:94][cH:95][cH:96][cH:97]1)[CH:98]=[CH:99][c:100]1[cH:101][cH:102][cH:103][cH:104][cH:105]1.[Pd:50].[Pd:51]>>[c:8]1([NH:33][CH2:34][CH2:35][C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[cH:9][cH:10][c:11](-[c:14]2[s:15][c:16]3[n:17][c:18]([C:23]4([c:26]5[cH:27][cH:28][cH:29][cH:30][cH:31]5)[CH2:24][CH2:25]4)[cH:19][cH:20][c:21]3[n:22]2)[cH:12][cH:13]1