Dichloromethane → tert-butyl (NE)-N-[[(9-bromo-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-2-carbonyl)amino]-methylsulfanylmethylidene]carbamate

HRID 821455Notes

Reaction equation

HRID 821455 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([cH:17][cH:18]1)-[c:6]1[n:7]([cH:11][c:12]([C:14](=[O:15])[OH:16])[n:13]1)[CH2:8][CH2:9][O:10]2.[C:19](=[O:20])([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[NH:26][C:27](=[NH:28])[S:29][CH3:30].[CH:55]([N:56]([CH2:57][CH3:58])[CH:59]([CH3:60])[CH3:61])([CH3:62])[CH3:63].[Cl:64][CH2:65][Cl:66].[P-:31]([F:32])([F:33])([F:34])([F:35])([F:36])[F:37].[n:38]1([O:39][C:40]([N:41]([CH3:42])[CH3:43])=[N+:44]([CH3:45])[CH3:46])[c:47]2[n:48][cH:49][cH:50][cH:51][c:52]2[n:53][n:54]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([cH:17][cH:18]1)-[c:6]1[n:7]([cH:11][c:12]([C:14](=[O:16])[N:28]=[C:27]([NH:26][C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[S:29][CH3:30])[n:13]1)[CH2:8][CH2:9][O:10]2

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 582043519-Bromo-5,6-dihydrobenzo[F]imidazo[1,2-D][1,4]oxazepine-2-carboxylic acidHCID 137319820tert-butyl N-[(methylsulfanyl)methanimidoyl]carbamate

Product 1

HCID 178503947tert-butyl (NE)-N-[[(9-bromo-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-2-carbonyl)amino]-methylsulfanylmethylidene]carbamate

Sources & evidence

ORD record
ord-5be6c169845b43febbd24ea97a1932f6
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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