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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 821465Generated: October 27, 2026

Tetrahydrofuran → 4-Hydroxy-4-(6-methoxy-[1,5]naphthyridin-4-yl)-piperidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/821465

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Reactant8-Bromo-2-methoxy-1,5-naphthyridineHCID 53421617—
ReactantButyllithiumHCID 178418339—
Product4-Hydroxy-4-(6-methoxy-[1,5]naphthyridin-4-yl)-piperidine-1-carboxylic acid tert-butyl esterHCID 66954565—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-10f003edabc24158a602eb6d86a3d0b9
Source noteTest data from https://doi.org/10.1039/C8SC04228D