Tetrahydrofuran → 4-Hydroxy-4-(6-methoxy-[1,5]naphthyridin-4-yl)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][n:5][c:6]2[cH:7][cH:8][c:9]([O:12][CH3:13])[n:10][c:11]12.[C:19]([CH3:20])([CH3:21])([CH3:22])[O:23][C:24](=[O:25])[N:26]1[CH2:27][CH2:28][C:29](=[O:32])[CH2:30][CH2:31]1.[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:14][CH2:15][CH2:16][CH2:17][Li:18]>>[c:2]1([C:29]2([OH:32])[CH2:28][CH2:27][N:26]([C:24]([O:23][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:25])[CH2:31][CH2:30]2)[cH:3][cH:4][n:5][c:6]2[cH:7][cH:8][c:9]([O:12][CH3:13])[n:10][c:11]12Participants
5
Sources & evidence
- ORD record
- ord-10f003edabc24158a602eb6d86a3d0b9
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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