Propanal → 2-anilino-7-chloro-6-fluoro-5-(1-hydroxypropyl)-1-phenyl-1,8-naphthyridin-4(1H)-one

HRID 821471Notes

Reaction equation

[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH3:27][CH2:28][CH2:29][CH2:30][Li:31].[CH:32]([CH2:33][CH3:34])=[O:35].[NH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[n:9](-[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:10]2[n:11][c:12]([Cl:20])[c:13]([F:19])[cH:14][c:15]2[c:16](=[O:18])[cH:17]1>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[n:9](-[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:10]2[n:11][c:12]([Cl:20])[c:13]([F:19])[c:14]([CH:32]([CH2:33][CH3:34])[OH:35])[c:15]2[c:16](=[O:18])[cH:17]1