Hydrochloric Acid → 4-(4-Chlorophenyl)-3,3-dimethylpiperidin-4-ol

HRID 821638Notes

Reaction equation

HRID 821638 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([OH:23])[C:9]([CH3:21])([CH3:22])[CH2:10][N:11]([C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[ClH:24].[O:25]1[CH2:26][CH2:27][O:28][CH2:29][CH2:30]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([OH:23])[C:9]([CH3:21])([CH3:22])[CH2:10][NH:11][CH2:12][CH2:13]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 593412124-(4-Chloro-phenyl)-4-hydroxy-3,3-dimethyl-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 231311434-(4-Chlorophenyl)-3,3-dimethylpiperidin-4-ol

Sources & evidence

ORD record
ord-727d94de401744998113a7eaefdd6889
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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