HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-N-methoxy-N-methylpyridine-3-carboxamide → (5-Bromopyridin-3-yl)(7-tert-butyl-2-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-N-methoxy-N-methylpyridine-3-carboxamide | HCID 18472269 | — |
| Reactant | HCID 86672095 | HCID 86672095 | — |
| Product | (5-Bromopyridin-3-yl)(7-tert-butyl-2-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone | HCID 86672094 | — |
Reaction Steps
The title compound was prepared according to the method described for Preparation 28 using 7-tert-butyl-2-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine (see Preparation 63) and 5-bromo-N-methoxy-N-methylnicotinamide to afford the title compound as a brown oil in 36% yield, 2.1 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846698B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-c3181a4f09654b04a5470105e1c69a8e |
| Source note | uspto-grants-2014_09 |