HRID82185

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(CO[Si](C)(C)C(C)(C)C)(CO[Si](C)(C)C(C)(C)C)n1cc(I)c2cncnc21

HCID70817590

未命名化合物

结构：CON(C)C(=O)c1cncc(N=C(c2ccccc2)c2ccccc2)c1

HCID86672080

未命名化合物

PRODUCTS

生成物

结构：CC(CO[Si](C)(C)C(C)(C)C)(CO[Si](C)(C)C(C)(C)C)n1cc(C(=O)c2cncc(N=C(c3ccccc3)c3ccccc3)c2)c2cncnc21

HCID86672103

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the method described for Preparation 28 using 7-[2-{[tert-butyl(dimethyl)silyl]oxy}-1-({[tert-butyl(dimethyl)silyl]oxy}methyl)-1-methylethyl]-5-iodo-7H-pyrrolo[2,3-d]pyrimidine (Preparation 114) and 5-[(diphenylmethylene)amino]-N-methoxy-N-methylnicotinamide (Preparation 23) to afford the title compound as a yellow foam in 69% yield, 1.76 g.

WORKUP

后处理

customThe title compound was prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1bae474f8cab4773bb9858a711598b1c
来源数据集: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08846698B2
来源说明: uspto-grants-2014_09

反应 SMILES

[Si:1]([O:8][CH2:9][C:10]([N:21]1[C:25]2[N:26]=[CH:27][N:28]=[CH:29][C:24]=2[C:23](I)=[CH:22]1)([CH2:12][O:13][Si:14]([C:17]([CH3:20])([CH3:19])[CH3:18])([CH3:16])[CH3:15])[CH3:11])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[C:31]1([C:37](=[N:44][C:45]2[CH:46]=[N:47][CH:48]=[C:49]([CH:56]=2)[C:50](N(OC)C)=[O:51])[C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>>[Si:1]([O:8][CH2:9][C:10]([N:21]1[C:25]2[N:26]=[CH:27][N:28]=[CH:29][C:24]=2[C:23]([C:50]([C:49]2[CH:48]=[N:47][CH:46]=[C:45]([N:44]=[C:37]([C:38]3[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=3)[C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[CH:56]=2)=[O:51])=[CH:22]1)([CH2:12][O:13][Si:14]([C:17]([CH3:20])([CH3:19])[CH3:18])([CH3:16])[CH3:15])[CH3:11])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]