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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 82185Generated: October 27, 2026

HCID 70817590, compound → {7-[2-{[tert-Butyl(dimethyl)silyl]oxy}-1-({[tert-butyl(dimethyl)silyl]oxy}methyl)-1-methylethyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}{5-[(diphenylmethylene)amino]pyridin-3-yl}methanone

https://huagongshe.com/reaction/82185

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 70817590HCID 70817590—
Reactant5-((Diphenylmethylene)amino)-N-methoxy-N-methylnicotinamideHCID 86672080—
Product{7-[2-{[tert-Butyl(dimethyl)silyl]oxy}-1-({[tert-butyl(dimethyl)silyl]oxy}methyl)-1-methylethyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}{5-[(diphenylmethylene)amino]pyridin-3-yl}methanoneHCID 86672103—

Reaction Steps

The title compound was prepared according to the method described for Preparation 28 using 7-[2-{[tert-butyl(dimethyl)silyl]oxy}-1-({[tert-butyl(dimethyl)silyl]oxy}methyl)-1-methylethyl]-5-iodo-7H-pyrrolo[2,3-d]pyrimidine (Preparation 114) and 5-[(diphenylmethylene)amino]-N-methoxy-N-methylnicotinamide (Preparation 23) to afford the title compound as a yellow foam in 69% yield, 1.76 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846698B2
Source datasetuspto-grants-2014_09
ORD IDord-1bae474f8cab4773bb9858a711598b1c
Source noteuspto-grants-2014_09