Tetrahydrofuran → 3,4-dihydro-6-hydroxy-3-(1-phenylmethyl-4-piperidinyl)-2(1H)-quinazolinone
Reaction equation
[C:24](=[O:25])([c:26]1[nH:27][cH:28][cH:29][n:30]1)[c:31]1[nH:32][cH:33][cH:34][n:35]1.[NH2:1][c:2]1[c:3]([CH2:9][NH:10][CH:11]2[CH2:12][CH2:13][N:14]([CH2:17][c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[CH2:15][CH2:16]2)[cH:4][c:5]([OH:8])[cH:6][cH:7]1.[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[NH:1]1[c:2]2[c:3]([cH:4][c:5]([OH:8])[cH:6][cH:7]2)[CH2:9][N:10]([CH:11]2[CH2:12][CH2:13][N:14]([CH2:17][c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[CH2:15][CH2:16]2)[C:24]1=[O:25]Participants
4
Sources & evidence
- ORD record
- ord-b2c668759cee48eeaf46ea53de04daf7
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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